Short Course Description
The course covers topics related to bacterial pathogenesis systems and the ways by which bacteria manipulate their host cells. The course introduces approaches by which bacterial pathogenesis systems (such as Type-3 secretion system, Type-4 secretion system, actin polymerization and others) are being studied and the ways by which these systems function. The course focuses on human bacterial pathogens such as: Yersinia, Salmonella, Legionella, Listeria and others. The genes associated with the pathogenicity of these bacteria, and the function of these gene products during the infection of host cell will be described in detail. In addition, methodologies used to identify virulence genes such as in-vivo expression technology (IVET), signature tagged mutagenesis (STM) and others are described as well as the used of whole genome sequencing to identify pathogenesis related genes.
Full syllabus will be available to registered students only