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Syllabus

Course Number 0455-3798-01
Course Name Molecular Signaling
Academic Unit The George S. Wise Faculty of Life Sciences -
Biology
Lecturer Prof. Ronit KramarskiContact
Contact Email: lironit@tauex.tau.ac.il
Office Hours By appointmentBuilding: Sherman - Life Sciences , Room: 717
Mode of Instruction Lecture
Credit Hours 2
Semester 2020/1
Day Mon
Hours 12:00-14:00
Building
Room
Syllabus Not Found

Short Course Description


Molecular Signaling

*How the cell sense the environment
*Receptors and Ligands that mediate signaling
*Molecular structure of Receptors and Ligands
*Receptors with enzymatic activities
*Growth Factors: NGF and Neurotrophic factors: structure and function.
*Receptor Tyrosine Kinases: Nomenclature, structure and function, ligand
binding, dimerization, signaling pathways, involvement in cancer.
* Non receptor tyrosine kinases
*G-protein coupled receptors: structure, functions and signaling pathways.
*Small G-proteins (Ras, Rho)
*Signaling pathways: PLC, PI3K, MapK
*regulation of the cytoskeleton organization
*Regulation of cell death, survival and development by autophagy
* Cell death ( apoptosis) induction of apoptosis by death receptors.
*Bcl-2 family of proteins.
*Caspases


The grade will be determined by a Seminar paper which will be also presented as a lecture to the whole class (the topic will be determined in agreement with the lecturer).



Full syllabus will be available to registered students only
Course Requirements

Students may be required to submit additional assignments
Full requirements as stated in full syllabus

The specific prerequisites of the course,
according to the study program, appears on the program page of the handbook



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