Short Course Description
The course will describe methodological approached used in neuropathologic investigations and diagnostics of a variety of brain diseases. It will cover basic neuropathology from tissue reactions in the brain, stroke, trauma, vascular problems and clinical neuropathology from neurodegenerative diseases, such as Alzheimer?s disease and other dementias, metabolic diseases, inflammatory diseases, such as Multiple sclerosis, infectious diseases, such as Creutzfeldt-Jakob disease and viral infections, malformations of the nervous system to brain tumour pathology. It will cover the molecular mechanisms underlying these diseases and present the models of these diseases in research.
The course will describe the background of nervous system diseases and introduce microscopic methods to determine nervous system changes in human brain and mouse models. It will furthermore present strategies for treatment development and translational research as well as pharmacological strategies.
The course will also introduce machine learning-assisted (AI ? artificial intelligence) analyses of brain slices using specific tissue stains (immunohistochemistry, immunofluorescence, specific dyes) and H&E.
Full Syllabus
